Does 7-KETO™ DHEA convert to DHEA? To Estrogen or Testosterone?
It does not actually convert to DHEA in the body, but its structural similarities to DHEA may result in a "cross-reactivity" with serum or salivary assays and result in what appears to be a higher DHEA level. (1)
Furthermore, 7-KETO does not convert to estrogen or testosterone. (2-4)
What Type of Support Does 7-KETO™ DHEA Provide?
In part, the role of 7-KETO involves supporting thermogenic enzymes that provide a pathway for heat production and energy burning (5-7), which may be helpful for promoting weight loss. In studies, 200 mg of 7-KETO per day combined with exercise was shown to support weight loss (5). This is the primary context in which 7-KETO is used.
Research on the role of 7-KETO in immune, cognitive and other areas of support similar to DHEA has proved promising but preliminary (1). In these cases, 7-KETO can be combined with regular DHEA. For instance, DHEA may be recommended at doses of 5-50 mg per day and combined with 50 to 200 mg per day of 7-KETO. It is safe to take them together unless the dose of DHEA starts to exceed 50 mg per day after which there may be some hormone related side effects (1).
What is the Source of 7-KETO™?
7-KETO is made from pharmaceutical grade DHEA. DHEA is produced when diosgenin is extracted from wild yam and modified in a laboratory process to achieve the final structure.
Are there any Side-Effects or Adverse Interactions?
7-KETO has few if any adverse events reported on it. The only frequently reported side effect is "vivid" dreams if taken too close to bedtime (1).
7-KETO may be safely taken over the long-term. The only medication that might involve a potential interaction is Coumadin (a blood thinner). 7-KETO has been shown to promote healthy platelet function and using the two together may have a synergistic blood-thinning effect (1).
