OptiBerry™ Educational Handout
What Is It?
OptiBerry™ is a concentrated, standardized blend of blueberry, strawberry, cranberry, bilberry, elderberry, and raspberry extracts and powders. It provides highly bioactive anthocyanins, including malvidin, cyanidin, delphinidin, and petunidin for enhanced antioxidant protection and healthy cardiovascular, skin, cellular and cognitive function.*
Uses For OptiBerry™
- Enhanced Antioxidant Protection: A clinical trial conducted at the Tufts University USDA Jean Mayer Human Nutrition Research Center (HNRC) on Aging involving elderly women reported that consumption of strawberries, containing a high level of antioxidant phenolic compounds, helped support healthy serum antioxidant capacity. The enhanced antioxidant protection, provided by the numerous anthocyanins and phenolics contained in this supplement, plays a key role in the rest the functions listed below.*
- Cardiovascular Support: A study performed at the Ohio State University Medical Center indicated that OptiBerry may provide vascular support by promoting healthy cellular immune mediator activity. Another study reported that a concentrated bilberry extract provided support for healthy vascular system function.*
- Skin Support: Research performed at the Ohio State University Medical Center reported that OptiBerry helped to support healthy skin by maintaining healthy immune mediator activity in human keratinocytes.*
- Healthy Cellular Function: Through the use of an accelerated neuronal aging model, another study performed at the Tufts University HNRC showed that the antioxidants found in blueberry and strawberry extracts provide protective support for central nervous system (CNS) function. Another study performed at Tufts supports this finding citing that potent phenolics such as those found in blueberry and strawberry extracts provided neural antioxidant protection.*
- Healthy Cognitive Function: An animal study performed, again, at the Tufts University HNRC demonstrated through a series of tests that the high antioxidant activity of berry extracts, such as strawberry and blueberry, may defend against age-related neuronal and cognitive decline.*
What Is The Source?
This formula contains: blueberry (Vaccinium angustifolium) (fruit), strawberry (Fragaria chiloensis) (fruit), cranberry (Vaccinium macrocarpon)(fruit), bilberry (Vaccinium myritillus) (fruit), elderberry (Sambucus nigra) (fruit), and raspberry (Rubus idaeus) (seed) extracts and powders. Optiberry™ is a registered trademark of InterHealth, N. I.
Recommendations
Pure Encapsulations recommends 1-2 capsules per day (50 mg each), in divided doses, with or between meals.
Are There Any Side Effects Or Precautions?
At this time, there are no known side effects or precautions. If pregnant or lactating, consult your physician before taking this product.
Are There Any Potential Adverse Drug Interactions?
At this time, there are no known adverse reactions when taken in conjunction with medications.
References:
1. Atalay M, Gordillo G, Roy S, Rovin B, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berry in a model of hemangioma. FEBS Lett 2003 Jun 5;544(1-3):252-7.
2. Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res 2002 Sep;36(9):1023-31.
3. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radic Biol Med 2000 Jul 1;29(1):51-60.
4. Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ,
Bickford PC. Reversals of age-related declines in neuronal signal transduction,
cognitive, and motor behavioral deficits with blueberry,spinach, or strawberry dietary supplementation. J Neurosci 1999 Sep 15;19(18):8114-21.
5. Joseph JA, Denisova NA, Bielinski D, Fisher DR, Shukitt-Hale B. Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention. Mech Ageing Dev 2000 Jul 31;116(2-3):141-53.
6. Joseph JA, Denisova N, Fisher D, Shukitt-Hale B, Bickford P, Prior R, Cao G. Membrane and receptor modifications of oxidative stress vulnerability in aging. Nutritional considerations. Ann N Y Acad Sci 1998 Nov 20;854:268-76.
7. Detre Z, Jellinek H, Miskulin M, Robert AM. Studies on vascular permeability in hypertension: action of Anthocyanosides. Clin Physiol Biochem 1986;4(2):143-9.
8. Narayan MS, Naidu KA, Ravishankar GA, Srinivas L, Venkataraman LV. Antioxidant effect of anthocyanin on enzymatic and non-enzymatic lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids 1999 Jan;60(1):1-4.
9. Healthnotes Clinical Essentials. Copyright 2003. Healthnotes, Inc.
For educational purposes only. Consult your physician for any health problems.
*This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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